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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name hsa-miR-126
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line human microvascular endothelial cells (HMECs)
Methods transfection, tube formation assay, scratch wound assay, qPCR, Western blot
Expression pattern down-regulated
Functional description Transfection of miR-126 reduced the HMECs 2D-capillary-like tube formation (p < 0.01) and migration (p < 0.01).
PubMed ID 27338342
Year 2016
Title miR-126 Regulation of Angiogenesis in Age-Related Macular Degeneration in CNV Mouse Model.
Drug-related ncRNA NO

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